Phenylpropanoids and polyketides
Sigma Aldrich Fine Chemicals Biosciences 3-Phenylpropionic acid 99%, FG | 501-52-0 | MFCD00002771 | 1KG
3-Phenylpropionic acid 99%, FG | Purity: 99% | Mol Wt: 150.17 | 501-52-0 | MFCD00002771 | 1KG
Sigma Aldrich Fine Chemicals Biosciences Tesaglitazar >=98% (HPLC) | 251565-85-2 | MFCD07784004 | 5MG
Tesaglitazar >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 408.47 | 251565-85-2 | MFCD07784004 | 5MG
Sigma Aldrich Fine Chemicals Biosciences Quercetin >=95% (HPLC), solid | 117-39-5 | 100G
Quercetin >=95% (HPLC), solid | Purity: >=95% (HPLC) | Mol Wt: 302.24 | 117-39-5 | 100G
Sigma Aldrich Fine Chemicals Biosciences Tesaglitazar >=98% (HPLC) | 251565-85-2 | MFCD07784004 | 25MG
Tesaglitazar >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 408.47 | 251565-85-2 | MFCD07784004 | 25MG
Apexbio Technology LLC Tacrolimus monohydrate 109581-93-3 1g
Tacrolimus monohydrate also identified as FK506 monohydrate is a macrolide immunosuppressive compound functioning via inhibition of calcineurin-mediated signaling pathways Specifically tacrolimus forms a complex with FK506-binding protein (FKBP12) subsequently blocking calcineurin phosphatase activity thus suppressing T-cell activation and diminishing interleukin-2 (IL-2) transcription levels In cellular assays tacrolimus demonstrates inhibition of calcineurin with IC50 values typically ranging between 0 1-1 0 nM Due to its targeted modulation of immune signaling this compound remains widely utilized in biomedical research particularly for investigations related to immune response mechanisms autoimmune disorder models transplantation biology and signal transduction pathways relevant to lymphocyte activation and cytokine expression
Sigma Aldrich Fine Chemicals Biosciences Phloretin >=99% | 60-82-2 | MFCD00002288 | 250MG
Phloretin >=99% | Purity: >=99% | Mol Wt: 274.27 | 60-82-2 | MFCD00002288 | 250MG
Medchemexpress LLC 5Z-7-oxozeaenol | 253863-19-3 | MFCD12912700 | 99.6% | 362.37 g/mol | C19H22O7 | 5 MG
5Z-7-Oxozeaenol is a natural, fungal-derived small molecule that acts as a potent, irreversible, and selective inhibitor of TAK1 and VEGF-R2. It is used in biochemical and cellular research to probe TAK1- and VEGFR2-mediated signaling; reported IC50 values are 8 nM for TAK1 and 52 nM for VEGF-R2. The compound is supplied as a solid with high purity suitable for research applications.
- Potent, irreversible inhibition of TAK1 (IC50 = 8 nM).
- Selective activity against VEGF-R2 (IC50 = 52 nM).
- High purity suitable for biochemical and cellular assays.
- Solid form convenient for handling and storage.
- Useful for studying MAPKKK-mediated signaling pathways.
Sigma Aldrich Fine Chemicals Biosciences Myricetin >=96.0% (HPLC) | 529-44-2 | MFCD00006827 | 25MG
Myricetin >=96.0% (HPLC) | Purity: >=96.0% (HPLC) | Mol Wt: 318.24 | 529-44-2 | MFCD00006827 | 25MG
Medchemexpress LLC Avobenzone | 70356-09-1 | 98.0% | 5 G
Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. It is also an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist.
- Promotes adipogenesis in hBM-MSCs
- Up-regulates mRNA levels of PPARγ during adipogenesis
- Inhibits proliferative activities of human trophoblast cells
- Induces apoptosis in HTR8/SVneo cells
- Shows weak ERα agonism and weak AR antagonism
Cayman Chemical 5Z 11Z 15R15HydroxyeIcosa
A stable isomer of 15(S)-HETE that elicits contraction of isolated pulmonary arteries from rabbits and inhibits the proliferation and migration of PC-3 cells
AARON CHEMICALS LLC SODIUM 8 2 HYDROXYBENZOYL 100G
sodium 8-[(2-hydroxybenzoyl)amino]octanoate, 100g
Medchemexpress LLC Cinnamyl alcohol | 104-54-1 | MFCD00002921 | 99.8% | 134.18 g/mol | C9H10O | 250g
Cinnamyl Alcohol is an active component from chestnut flower inhibits increased PPAR expression exhibits anti-obesity antioxidant and anti-inflammatory activities[1]
Sigma Aldrich Fine Chemicals Biosciences Scopoletin >=99% | 92-61-5 | MFCD00006872 | 100MG
Scopoletin >=99% | Purity: >=99% | Mol Wt: 192.17 | 92-61-5 | MFCD00006872 | 100MG